Facilitated Secretion of Pressor Amounts of Vasopressin in Spontaneously Hypertensive Rats

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タイトル ( eng )
Facilitated Secretion of Pressor Amounts of Vasopressin in Spontaneously Hypertensive Rats
タイトル ( jpn )
高血圧自然発症ラットにおける昇圧量パゾプレシン分泌の促進
作成者
Iriuchijima Juro
収録物名
Hiroshima Journal of Medical Sciences
33
4
開始ページ 571
終了ページ 575
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
Vasopressin antagonist, which antagonizes pressor effect of vasopressin, was injected to spontaneously hypertensive rats under various conditions to observe whether arterial pressure was decreased to indicate secretion of pressor amounts of vasopressin. Vasopressin was secreted in pressor amounts in spontaneously hypertensive rats after acute spinal transection or sinoaortic denervation. This is in sharp contrast to normal rats in which ganglion blockade with hexamethonium bromide is necessary in addition to spinal transection or sinoaortic denervation for secretion of pressor amounts of vasopressin. This indicates that vasopressin secretion in pressor amounts is faciliated in spontaneously hypertensive rats.
著者キーワード
Spontaneously hypertensive rat
SHR
Vasopressin
Baroreceptor
Volume receptor
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1984-12
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6549509