Facilitated Secretion of Pressor Amounts of Vasopressin in Spontaneously Hypertensive Rats
Hiroshima Journal of Medical Sciences Volume 33 Issue 4
Page 571-575
published_at 1984-12
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| File | |
| Title ( eng ) |
Facilitated Secretion of Pressor Amounts of Vasopressin in Spontaneously Hypertensive Rats
|
| Title ( jpn ) |
高血圧自然発症ラットにおける昇圧量パゾプレシン分泌の促進
|
| Creator |
Iriuchijima Juro
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 33 |
| Issue | 4 |
| Start Page | 571 |
| End Page | 575 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
Vasopressin antagonist, which antagonizes pressor effect of vasopressin, was injected to spontaneously hypertensive rats under various conditions to observe whether arterial pressure was decreased to indicate secretion of pressor amounts of vasopressin. Vasopressin was secreted in pressor amounts in spontaneously hypertensive rats after acute spinal transection or sinoaortic denervation. This is in sharp contrast to normal rats in which ganglion blockade with hexamethonium bromide is necessary in addition to spinal transection or sinoaortic denervation for secretion of pressor amounts of vasopressin. This indicates that vasopressin secretion in pressor amounts is faciliated in spontaneously hypertensive rats.
|
| Keywords |
Spontaneously hypertensive rat
SHR
Vasopressin
Baroreceptor
Volume receptor
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University School of Medicine
|
| Date of Issued | 1984-12 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6549509
|
