High-dose Intravenous Immunoglobulin for Myasthenia Gravis

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タイトル ( eng )
High-dose Intravenous Immunoglobulin for Myasthenia Gravis
作成者
Sakano Takashi
Hamasaki Takashi
Shimizu Hiroshi
Harada Yoshiaki
Ueda Kazuhiro
収録物名
Hiroshima Journal of Medical Sciences
37
1
開始ページ 7
終了ページ 9
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
A 7-year-old girl with ocular myasthenia gravis (MG) refractory to prednisolone and anticholinesterase compounds was treated with high-dose intravenous immunoglobulin (IVIg). Ocular symptoms disappeared rapidly by the administration of IVIg 300 mg/kg/day for five consecutive days. Booster infusions of IVIg at an interval of 2 weeks appeared to be effective in maintaining a remission at least as an adjunct to prednisolone. The levels of acetylcholine receptor (AchR) antibodies were not correlated with clinical improvement or aggravation. Thus, high-dose IVIg may be useful in refractory cases of MG, allowing a reduction in doses of immunosuppressive drugs.
著者キーワード
Intravenous immunoglobulin
Myasthenia gravis
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University Medical Press
発行日 1988-03
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3410736