High-dose Intravenous Immunoglobulin for Myasthenia Gravis
Hiroshima Journal of Medical Sciences Volume 37 Issue 1
Page 7-9
published_at 1988-03
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| File | |
| Title ( eng ) |
High-dose Intravenous Immunoglobulin for Myasthenia Gravis
|
| Creator |
Sakano Takashi
Hamasaki Takashi
Shimizu Hiroshi
Harada Yoshiaki
Ueda Kazuhiro
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 37 |
| Issue | 1 |
| Start Page | 7 |
| End Page | 9 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
A 7-year-old girl with ocular myasthenia gravis (MG) refractory to prednisolone and anticholinesterase compounds was treated with high-dose intravenous immunoglobulin (IVIg). Ocular symptoms disappeared rapidly by the administration of IVIg 300 mg/kg/day for five consecutive days. Booster infusions of IVIg at an interval of 2 weeks appeared to be effective in maintaining a remission at least as an adjunct to prednisolone. The levels of acetylcholine receptor (AchR) antibodies were not correlated with clinical improvement or aggravation. Thus, high-dose IVIg may be useful in refractory cases of MG, allowing a reduction in doses of immunosuppressive drugs.
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| Keywords |
Intravenous immunoglobulin
Myasthenia gravis
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University Medical Press
|
| Date of Issued | 1988-03 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3410736
|
