Nephrotoxicity of Pyrroloquinoline Quinone in Rats
Hiroshima Journal of Medical Sciences Volume 38 Issue 1
Page 49-51
published_at 1989-03
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| File | |
| Title ( eng ) |
Nephrotoxicity of Pyrroloquinoline Quinone in Rats
|
| Creator |
Watanabe Akiharu
Hobara Norio
Ohsawa Toshiya
Higashi Toshihiro
Tsuji Takao
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 38 |
| Issue | 1 |
| Start Page | 49 |
| End Page | 51 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
When pyrroloquinoline quinone (PQQ) was intraperitoneally injected into rats daily for 4 days at a dose of 11.5 mg/kg body weight/injection, functional and morphologic changes of the kidneys were clearly observed. The most prominent finding was necrotic and degenerative changes of the proximal tubular epithelium as well as hematuria and an elevation of serum creatinine concentration.
|
| Keywords |
Nephrotoxicity
Pyrroloquinoline quinone
Renal tubules
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University Medical Press
|
| Date of Issued | 1989-03 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 2546903
|
