Lymphocyte Subpopulations in Peripheral Blood and the Spleen from Gastric Cancer Patients
Hiroshima Journal of Medical Sciences 39 巻 2 号
23-27 頁
1990-06 発行
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| ファイル情報(添付) | |
| タイトル ( eng ) |
Lymphocyte Subpopulations in Peripheral Blood and the Spleen from Gastric Cancer Patients
|
| 作成者 |
Kuroi Katsumasa
Sato Yukio
Takayama Takahiko
Baba Nobutoshi
Yamaguchi Yoshiyuki
Toge Tetsuya
|
| 収録物名 |
Hiroshima Journal of Medical Sciences
|
| 巻 | 39 |
| 号 | 2 |
| 開始ページ | 23 |
| 終了ページ | 27 |
| 収録物識別子 |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| 抄録 |
Lymphocyte subpopulations in peripheral blood and the spleen from gastric cancer patients were identified by either single or two color analysis with fluorescence activated cell sorter-IV (FACS-IV) using monoclonal antibodies. The absolute and percentages of CD3+ (mature T) cells and CD4 + (helper/inducer T) cells in peripheral blood from the advanced cancer patients were significantly lower than those from normal healthy controls. In peripheral blood, a significant decrease of CD4 + cells was due to the decrease of CD4 + CD45RA + (suppressor inducer T) cells, while CDS+ CD11b+ (suppressor T) cells tended to increase with progress of the disease. CD4+ CD45RA + cells located more predominantly in peripheral blood and spleen than in the splenic vein, while CDS+ CD11b+ cells were more predominant in the splenic vein.
|
| 著者キーワード |
Gastric cancer
Lymphocyte subpopulations
Peripheral blood
Spleen
Monoclonal antibodies
|
| NDC分類 |
医学 [ 490 ]
|
| 言語 |
英語
|
| 資源タイプ | 紀要論文 |
| 出版者 |
Hiroshima University Medical Press
|
| 発行日 | 1990-06 |
| 出版タイプ | Version of Record（出版社版。早期公開を含む） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 2228724
|
