Spontaneous mutations affecting glycerol-3-phosphate dehydrogenase enzyme activity in Drosophila melanogaster

The Japanese Journal of Genetics 67 巻 2 号 125-132 頁 1992-04-25 発行
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タイトル ( eng )
Spontaneous mutations affecting glycerol-3-phosphate dehydrogenase enzyme activity in Drosophila melanogaster
タイトル ( jpn )
キイロショウジョウバエのグリセロ-ル-3-リン酸脱水素酵素活性に関与する自然発生突然変異
作成者
Koga Akihiko
Harada Ko
Mukai Terumi
収録物名
The Japanese Journal of Genetics
67
2
開始ページ 125
終了ページ 132
抄録
Significant genetic variance in glycerol-3-phosphate dehydrogenalse (GPDH) activity was observed between chromosome lines of Drosophila melanogaster that had each accumulated spontaneous mutations for approximately 300 generations. No restriction map variation was found in a 26-kb region surrounding the entire Gpdh gene. The restriction analysis used is capable of detecting insertions/deletions larger than 0.05 kb. The survey would also detect chromosomal recombinations that include the entire Gpdh coding region. Therefore, if the spontaneous mutations that affected the enzyme activity are located inside the Gpdh gene region, then they are base pair substitutions or structural changes that are smaller than the limit in resolution described above.
NDC分類
生物科学・一般生物学 [ 460 ]
言語
英語
資源タイプ 学術雑誌論文
出版者
日本遺伝学会
発行日 1992-04-25
権利情報
Copyright (c) 1992 日本遺伝学会
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0021-504X
[DOI] 10.1266/jjg.67.125
[NCID] AA00690924
[DOI] http://dx.doi.org/10.1266/jjg.67.125