Spontaneous mutations affecting glycerol-3-phosphate dehydrogenase enzyme activity in Drosophila melanogaster
The Japanese Journal of Genetics Volume 67 Issue 2
Page 125-132
published_at 1992-04-25
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| File | |
| Title ( eng ) |
Spontaneous mutations affecting glycerol-3-phosphate dehydrogenase enzyme activity in Drosophila melanogaster
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| Title ( jpn ) |
キイロショウジョウバエのグリセロ-ル-3-リン酸脱水素酵素活性に関与する自然発生突然変異
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| Creator |
Koga Akihiko
Harada Ko
Mukai Terumi
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| Source Title |
The Japanese Journal of Genetics
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| Volume | 67 |
| Issue | 2 |
| Start Page | 125 |
| End Page | 132 |
| Abstract |
Significant genetic variance in glycerol-3-phosphate dehydrogenalse (GPDH) activity was observed between chromosome lines of Drosophila melanogaster that had each accumulated spontaneous mutations for approximately 300 generations. No restriction map variation was found in a 26-kb region surrounding the entire Gpdh gene. The restriction analysis used is capable of detecting insertions/deletions larger than 0.05 kb. The survey would also detect chromosomal recombinations that include the entire Gpdh coding region. Therefore, if the spontaneous mutations that affected the enzyme activity are located inside the Gpdh gene region, then they are base pair substitutions or structural changes that are smaller than the limit in resolution described above.
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| NDC |
Biology [ 460 ]
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| Language |
eng
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| Resource Type | journal article |
| Publisher |
日本遺伝学会
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| Date of Issued | 1992-04-25 |
| Rights |
Copyright (c) 1992 日本遺伝学会
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| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0021-504X
[DOI] 10.1266/jjg.67.125
[NCID] AA00690924
[DOI] http://dx.doi.org/10.1266/jjg.67.125
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