Spontaneous mutations affecting glycerol-3-phosphate dehydrogenase enzyme activity in Drosophila melanogaster

The Japanese Journal of Genetics Volume 67 Issue 2 Page 125-132 published_at 1992-04-25
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Title ( eng )
Spontaneous mutations affecting glycerol-3-phosphate dehydrogenase enzyme activity in Drosophila melanogaster
Title ( jpn )
キイロショウジョウバエのグリセロ-ル-3-リン酸脱水素酵素活性に関与する自然発生突然変異
Creator
Koga Akihiko
Harada Ko
Mukai Terumi
Source Title
The Japanese Journal of Genetics
Volume 67
Issue 2
Start Page 125
End Page 132
Abstract
Significant genetic variance in glycerol-3-phosphate dehydrogenalse (GPDH) activity was observed between chromosome lines of Drosophila melanogaster that had each accumulated spontaneous mutations for approximately 300 generations. No restriction map variation was found in a 26-kb region surrounding the entire Gpdh gene. The restriction analysis used is capable of detecting insertions/deletions larger than 0.05 kb. The survey would also detect chromosomal recombinations that include the entire Gpdh coding region. Therefore, if the spontaneous mutations that affected the enzyme activity are located inside the Gpdh gene region, then they are base pair substitutions or structural changes that are smaller than the limit in resolution described above.
NDC
Biology [ 460 ]
Language
eng
Resource Type journal article
Publisher
日本遺伝学会
Date of Issued 1992-04-25
Rights
Copyright (c) 1992 日本遺伝学会
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0021-504X
[DOI] 10.1266/jjg.67.125
[NCID] AA00690924
[DOI] http://dx.doi.org/10.1266/jjg.67.125