HAIRY CELL LEUKEMIA (HCL) の 12 症例の細胞学的解析
広島大学総合科学部紀要. IV, 理系編 Volume 26
Page 63-70
published_at 2000-12-28
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| File | |
| Title ( jpn ) |
HAIRY CELL LEUKEMIA (HCL) の 12 症例の細胞学的解析
|
| Title ( eng ) |
Cytology in Hairy Cell Leukemia (HCL)
|
| Creator |
Izumi Takaki
Komura Takashi
Kushima Kimio
Yamashita Misako
Tanaka Kimio
|
| Contributors | 国立情報学研究所 |
| Source Title |
広島大学総合科学部紀要. IV, 理系編
Memoirs of the Faculty of Integrated Arts and Sciences, Hiroshima University. IV, Science reports
|
| Volume | 26 |
| Start Page | 63 |
| End Page | 70 |
| Abstract |
Hairy cell leukemia (HCL) is a chronic lympho-proliferative disease. The disease is clinically characterized by anemia, granulocytopenia, thrombocytopenia, monocytopenia, splenomegaly. This leukemia cells have peculiar shape with hairlike projection, and express mature B-cell antigens such as, CD19,CD20 and Ig heavy chain on their surface. Nuclear and cytoplasm area ratio was low. Cell biological observation and chromosome analysis were performed in 12 patients. Translocation at 14q32 was found in 2 patients and loss of chromosome 6 was found in one patient. These cytogenetical results suggest taht HCL is different disease from chronic lymphocytic leukemia.
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| Keywords |
Hairy cell leukemia
B-cell
chromosome aberrations
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
jpn
|
| Resource Type | departmental bulletin paper |
| Publisher |
広島大学総合科学部
|
| Date of Issued | 2000-12-28 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Date |
[Created] 2006-03-21
|
| Source Identifier |
[ISSN] 1340-8364
[NCID] AN10435936
|
