The occurrence of alopecia was surveyed to devise some care technique which may prevent or reduce scalp hair loss seen in Very low birth weight infants. The subjects were 30 Very low birth weight infants admitted to the NICU, with 24-32 weeks gestation and birth weight 568-1364 g. Occurrence of alopecia was observed and recorded chronologically from time of admittance. Results. 1) Although low birth weight infants showed tendency for hair loss. no relationship was observed between birth weight and hair loss. 2) Although a relationship was observed between endotracheal intubation and hair loss. there was no correlation to the number of days of intubation. 3) A relationship was observed between the use of donut-shaped cushion for the head and hair loss. 4) For body position, a relationship was observed between supine position. in comparison to other positions, and hair loss. 5) A relationship was observed between the insertion of central venous catheter (umbilical catheter) and hair loss. In summary. constant or restrained body position due to endotracheal intubation or central venous catheter compressed the scalp and contributed to hair loss. By using donut-shaped cushion, the part that constantly contacted the cushion was compressed and hair loss occurred in that area. As limitation of this study, we were unable to investigate the individual systematic conditions such as stress or circulatory dynamics after birth.