A Semantic Similarity Measurement Method Based on Information Quality in the Structure of the Gene Ontology

5th International Workshop on Computational Intelligence & Applications Proceedings : IWCIA 2009 Page 117-121 published_at 2009-11
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Title ( eng )
A Semantic Similarity Measurement Method Based on Information Quality in the Structure of the Gene Ontology
Creator
Hirai Junya
Nishizaki Ichiro
Hayashida Tomohiro
Source Title
5th International Workshop on Computational Intelligence & Applications Proceedings : IWCIA 2009
Start Page 117
End Page 121
Abstract
Gene ontology (GO) which described a biological concept of gene has attracted attention as an index for measuring semantic similarity of gene. This paper considers a new method for measuring the semantic similarity of GO through an extension and combination of two existing methods by Resnik and Wang et al. in order to improve their drawbacks of effects of shallow annotation. It is shown that the proposed method is superior to existing methods through experiments with pathway data.
Keywords
gene ontology
semantic similarity
pathway
NDC
Technology. Engineering [ 500 ]
Language
eng
Resource Type conference paper
Publisher
IEEE SMC Hiroshima Chapter
Date of Issued 2009-11
Rights
(c) Copyright by IEEE SMC Hiroshima Chapter.
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 1883-3977
[URI] http://www.hil.hiroshima-u.ac.jp/iwcia/2009/