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ID 49941
file
creator
SUMII, Koji
SUMIOKA, Masaaki
HIRATA, Ken
UEMURA, Naomi
TARI, Akira
YOSHIHARA, Masaharu
SEKITO, Masaki
TOKUTOMI, Tadashi
INABA, Yoshirou
TESHIMA, Hitoshi
INBE, Akira
TOKUMO, Kenji
OHGOSHI, Hiroaki
HARUMA, Ken
KAJIYAMA, Goro
subject
Duodenal Ulcer
Antral somatostatin
Acidity
NDC
Medical sciences
abstract
The antral somatostatin contents were investigated in biopsy specimens of the antrum from normal subjects and patients with duodenal ulcer. There was good correlation (r=0.77044) between antral somatostatin contents and maximal acidity in normal subjects, but the correlation between antral somatostatin contents and maximal acid output was not significant (r=0.254367). This result may indicate that antral somatostatin content is regulated by intragastric pH in normal subjects. On the other hands, no correlation was observed between antral somatostatin contents and acidity or acid output in patients with duodenal ulcer.
Therefore the impaired regulation of acid on antral somatostatin contents could be one of the important factors in the pathogenesis of duodenal ulcer disease.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 35
issue
Issue 4
start page
343
end page
346
date of issued
1986-12
publisher
Hiroshima University School of Medicine
issn
0018-2052
ncid
pubmed id
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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