A Clinicohistopathological Study of IgA Nephropathy Associated with Nephrotic Syndrome
Hiroshima Journal of Medical Sciences Volume 36 Issue 3
Page 261-265
published_at 1987-09
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Title ( eng ) |
A Clinicohistopathological Study of IgA Nephropathy Associated with Nephrotic Syndrome
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Creator |
YORIOKA Noriaki
WADA Koji
KANAHARA Koji
OGAWA Takahiko
TAKAHASHI Naoko
ODA Hiroaki
HIRABAYASHI Akira
KOBAYASHI Makoto
OKUSHIN Sayuri
YAMAKIDO Michio
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Source Title |
Hiroshima Journal of Medical Sciences
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Volume | 36 |
Issue | 3 |
Start Page | 261 |
End Page | 265 |
Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
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Abstract |
Among the 201 cases of IgA nephropathy, a study was made of the clinical characteristics, laboratory findings, and histopathological findings of 11 cases (5.5%) presenting nephrotic syndrome in comparison with those of a non-nephrotic group. The results of this study showed that in comparison with the non-nephrotic group the frequency of hypertension, anemia, and depressed renal function was higher in the nephrotic group and that the histological damage was severer. As can be expected, the frequency of severe proteinuria, hypoproteinemia, and depressed serum IgG value was higher in the nephrotic group, but no significant difference could be demonstrated in degree of hematuria, serum IgA value, and immunofluorescence findings. Furthermore, the response to various treatments was unfavorable and in 3 cases chronic renal failure developed. In general, in many of the cases the prognosis is poor.
On the other hand, the authors experienced one case with minimal change in the histological picture which responded favorably to steroid administration. The significance of such a case is yet unknown. |
Keywords |
IgA nephropathy
Nephrotic syndrome
Renal failure
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NDC |
Medical sciences [ 490 ]
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Language |
eng
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Resource Type | departmental bulletin paper |
Publisher |
Hiroshima University Medical Press
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Date of Issued | 1987-09 |
Publish Type | Version of Record |
Access Rights | open access |
Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3692889
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