Effect of General Anesthesia on Plasma Ascorbic Acid Level
Hiroshima Journal of Medical Sciences Volume 36 Issue 1
Page 69-73
published_at 1987-03
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| File | |
| Title ( eng ) |
Effect of General Anesthesia on Plasma Ascorbic Acid Level
|
| Creator |
AKITA Susumu
KAWAHARA Michio
TAKESHITA Takahisa
MORIO Michio
FUJII Kohyu
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 36 |
| Issue | 1 |
| Start Page | 69 |
| End Page | 73 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
Ascorbic acid (AsA) and dehydroascorbic acid (DHA) in plasma, and the total vitamin C (AsA + DHA) in urine after oral surgery were measured to investigate whether general anesthesia has effects on the level of plasma AsA. Plasma AsA decreased significantly on the 1st and 3rd post-operative day in the general anesthesia group, but not in the local anesthesia group. A decrease in the AsA level was seen in both the halothane group and the neuroleptanesthesia group. Plasma DHA was not detected pre-operatively, but increased post-operatively and the total vitamin C in the urine decreased on the 1st post-operative day in the general anesthesia group.
It was concluded that general anesthesia caused a decrease in the plasma AsA level. This can be only partially explained by the oxidation of AsA. We are going to investigate other causes as the degree of decrease of AsA was larger than the degree of increase of DHA. |
| Keywords |
General anesthesia
Local anesthesia
Plasma ascorbic acid
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University School of Medicine
|
| Date of Issued | 1987-03 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3583806
|
