Clinical Effects of Halothane Concentration on Trifluoroacetic Acid Excretion in Urine
Hiroshima Journal of Medical Sciences 34 巻 4 号
377-380 頁
1985-12 発行
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| ファイル情報(添付) | |
| タイトル ( eng ) |
Clinical Effects of Halothane Concentration on Trifluoroacetic Acid Excretion in Urine
|
| 作成者 |
TAKIYAMA Reiko
MORIO Michio
FUJII Kohyu
KIKUCHI Hirosato
YUGE Osafumi
CHIKASUE Fumihiko
TAIRA Yutaka
JORDANOV Jordan G.
|
| 収録物名 |
Hiroshima Journal of Medical Sciences
|
| 巻 | 34 |
| 号 | 4 |
| 開始ページ | 377 |
| 終了ページ | 380 |
| 収録物識別子 |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| 抄録 |
Excreted amount of urinary trifluoroacetic acid (TFA) during and after halothane anesthesia in twelve surgical patients was determined isotachophoretically. The levels of urinary TFA which amount was zero or a trace during the anesthesia increased after discontinuation of halothane inhalation. The values of daily excreted TFA were the highest on the 2.1±0.3 postoperative day (M±SEM). The urinary TFA values of patients inhaling a low concentration (0.8%) of halothane reverted to zero or a trace level on the 11.2±1.0 postoperative day (M±SEM) and the total amount of averaged 21.53 ± 3.23 mmol (M ± SEM). In patients to levels seen on the 7 .0 ± 0.6 postoperative day (M±SEM) and the total amount of TFA excreted was 20.20±4.77 mmol (M±SEM). These clinical findings indicate that the aerobic biotransformation of halothane after anesthesia is enhanced by high concentration of halothane.
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| 著者キーワード |
Halothane
Metabolism
Trifluoroacetic acid
Halothane concentration
|
| 内容記述 |
Supported in part by Research Grants No.57480297 and 57570564 from the Ministry of Education, Science and Culture, Japan.
Presented in part at the 7th World Congress of Anesthesiologists, Hamburg, September 1980. |
| NDC分類 |
医学 [ 490 ]
|
| 言語 |
英語
|
| 資源タイプ | 紀要論文 |
| 出版者 |
Hiroshima University School of Medicine
|
| 発行日 | 1985-12 |
| 出版タイプ | Version of Record（出版社版。早期公開を含む） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3830994
|
