Endocrine Profile in Rats with Postgastrectomy Malabsorption: a Pilot Study
Hiroshima Journal of Medical Sciences Volume 34 Issue 2
Page 209-213
published_at 1985-06
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| File | |
| Title ( eng ) |
Endocrine Profile in Rats with Postgastrectomy Malabsorption: a Pilot Study
|
| Creator |
KISHIMOTO Shinya
KONEMORI Reiko
KAMBARA Akihiko
OKAMOTO Kazuma
SHIMIZU Satoru
KOH Hassei
KUNITA Toshiro
DAITOKU Kunihiko
KAJIYAMA Goro
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 34 |
| Issue | 2 |
| Start Page | 209 |
| End Page | 213 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
Abnormal endocrine profile, especially in the enteropancreatic axis, was described in rats with malnutrition caused by malabsorption after total gastrectomy. Insulin, substance P and motilin concentrations at the fasting condition were significantly elevated in malnutritious rats after total gastrectomy when compared to those in control rats. A significant elevation of pancreatic glucagon and motilin was noted after intraduodenal fat administration in malnutritious rats. These data suggest that these peptides of many humoral factors may thus cause abnormal enteropancreatic axis and consequent malnutrition.
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| Keywords |
Postgastrectomy
Insulin
Pancreatic glucagon
Motilin
Substance P
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University School of Medicine
|
| Date of Issued | 1985-06 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 2411681
|
