Zinc, Copper, and Manganese Concentrations in Cerebrospinal Fluid of Patients with Viral Meningitis

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Title ( eng )
Zinc, Copper, and Manganese Concentrations in Cerebrospinal Fluid of Patients with Viral Meningitis
Creator
ISHIGAME Koichi
NISHI Yoshikazu
Source Title
Hiroshima Journal of Medical Sciences
Volume 34
Issue 1
Start Page 61
End Page 65
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
We investigated whether information on concentrations of the trace metals in cerebrospinal fluid of patients with viral meningitis could be of value in diagnosis or prognosis. Samples from ten patients and 11 control subjects were analysed for zinc, copper, and manganese by atomic absorption spectrophotometry method. Protein concentrations in cerebrospinal fluid were also determined. The mean pretreatment values of zinc and copper were significantly lower (p<0.05 and p<0.01, respectively) than those of control subjects and returned to the control value after treatment. The mean pretreatment value of manganese was significantly lower (p<0.001) than the control value and became still lower (p<0.01) after treatment. The estimation of the trace metals in cerebrospinal fluid of patients with viral meningitis is very helpful to determine the diagnosis and prognosis.
Keywords
Trace elements
Cerebrospinal fluid
Viral meningitis
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University School of Medicine
Date of Issued 1985-03
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 4019241