Evaluation of Outer Retinal Layer Thickness in Normal and Glaucomatous Eyes using Spectral Domain Optical Coherence Tomography

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Title ( eng )
Evaluation of Outer Retinal Layer Thickness in Normal and Glaucomatous Eyes using Spectral Domain Optical Coherence Tomography
Creator
Latief Miftahul Akhyar
Ibrahim Diah Gemala
Rimayanti Ulfah
Source Title
Hiroshima Journal of Medical Sciences
Volume 68
Issue 2-3
Start Page 19
End Page 26
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
Purpose: The purpose of this study was to examine the outer retinal layer thicknesses in normal and glaucomatous eyes with a Topcon 3D spectral domain optical coherence tomography (SD-OCT) instrument.
Methods: Fifty-nine normal eyes and 139 glaucomatous eyes were included in this study. The SD-OCT images were assessed to determine the overall average, superior, and inferior thicknesses of the inner and outer retinal layers. The macula was examined in an area of 7 × 7 mm centered on the fovea and divided into 10 × 10 grids. The thicknesses of the inner and outer macular layers in each square of the ten grids horizontally aligned below the fovea were plotted in a line graph.
Results: The findings indicated that all the inner retinal parameters decreased with increasing glaucoma severity. The difference in outer retinal layer thickness between the normal and all the glaucoma groups was not significant. However, the outer retinal layer thickness was significantly different for different glaucoma severity subgroups (P < 0.05). The changes in thickness in the outer retinal layer in the ten small squares horizontally aligned under the fovea revealed significant differences between the normal control group and the various glaucoma severity subgroups.
Conclusions: Changes in the thickness of the outer macular retinal layer can be detected using a Topcon 3D SD-OCT 2000. The findings of this study indicate that the outer retinal layer might be involved in glaucomatous eyes.
Keywords
Outer retinal layer thickness
inner retinal layer thickness
glaucoma
SD-OCT
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University Medical Press
Date of Issued 2019-09
Rights
Copyright (c) 2019 Hiroshima University Medical Press
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[ISSN] 2433-7668
[NCID] AA00664312
[DOI] 10.24811/hjms.68.2-3_19
[DOI] https://doi.org/10.24811/hjms.68.2-3_19