Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II

小胞体関連分解の抑制はムコ多糖症II型原因タンパク質変異型イズロン酸2スルファターゼの機能を回復する

尾﨑 陽介

英語

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Osaki et al. Cell Death and Disease (2018) 9:808

[DOI] https://doi.org/10.1038/s41419-018-0871-8

広島大学