Inactivation of the Influenza Virus by a Supplemental Fermented Plant Product (Manda Koso)
Hiroshima Journal of Medical Sciences Volume 66 Issue 4
Page 97-101
published_at 2017-12
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Title ( eng ) |
Inactivation of the Influenza Virus by a Supplemental Fermented Plant Product (Manda Koso)
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Creator |
Nomura Toshihito
Yoshimoto Reiko
Kawabata Ryoko
Matsubara Toshiki
Narai Seika
Oda Kosuke
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Source Title |
Hiroshima Journal of Medical Sciences
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Volume | 66 |
Issue | 4 |
Start Page | 97 |
End Page | 101 |
Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
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Abstract |
Manda Koso is a commercial fermented plant product (FPP) made from 53 types of fruits and vegetables that are fermented for more than 3 years. We hypothesized that the FPP can prevent infection by influenza virus and human norovirus. Therefore, we investigated the effects of the FPP on influenza virus and feline calicivirus, a surrogate of human norovirus. We found that 10% FPP inactivated the influenza virus but not the feline calicivirus. Inhibition of the influenza virus was highly concentration-dependent: 1% and 0.3% FPP showed reduced inactivation efficacy. The effects of the FPP on the influenza virus-infected cells were investigated by addition of the FPP to the culture medium after virus infection. No suppressive effect of the FPP on influenza replication in MDCK cells was observed. The results showed that the FPP could inactivate influenza virus by affecting the virus particles.
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Keywords |
anti-viral reagents
cytotoxicity
influenza virus
feline calicivirus
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NDC |
Medical sciences [ 490 ]
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Language |
eng
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Resource Type | departmental bulletin paper |
Publisher |
Hiroshima University Medical Press
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Date of Issued | 2017-12 |
Rights |
Copyright (c) 2017 Hiroshima University Medical Press
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Publish Type | Version of Record |
Access Rights | open access |
Source Identifier |
[ISSN] 0018-2052
[ISSN] 2433-7668
[NCID] AA00664312
[DOI] 10.24811/hjms.66.4_97
[DOI] https://doi.org/10.24811/hjms.66.4_97
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