Increase in Content and Release of Kallikreinogen in Acute Experimental Pancreatitis in Rats

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タイトル ( eng )
Increase in Content and Release of Kallikreinogen in Acute Experimental Pancreatitis in Rats
タイトル ( jpn )
実験的急性膵炎におけるカリクレイノーゲン増加
作成者
Takasugi Sumiyoshi
Kanno Tomio
収録物名
Hiroshima Journal of Medical Sciences
31
1
開始ページ 45
終了ページ 50
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
The content of kallikreinogen in the pancreas isolated from rats with acute experimental pancreatitis rose to over ten times the level in the control group. In the isolated and perfused pancreata prepared from the pancreatitis group; the "resting" leak of kallikreinogen into the portal perfusate was 8 times that in the control group, and it was further increased by stimulation with CCK (5 mU/ml). The "resting" amylase level in the portal perfusate was 5 times that in the control group, but stimulation with CCK caused no further increase. The results suggest that kallikrein formation may be an important step in the development of acute pancreatitis.
著者キーワード
Kallikrein
Acute pancreatitis
Closed-loop method
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1982-03-10
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6920376