Basic Study of Polyetherurethane Coated Bead-Type Activated Charcoal for Direct Hemoperfusion

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タイトル ( eng )
Basic Study of Polyetherurethane Coated Bead-Type Activated Charcoal for Direct Hemoperfusion
タイトル ( jpn )
ポリエーテル型ウレタン被覆ビーズ状活性炭を用いた血液直接灌流の基礎研究
作成者
Kawanishi Hideki
Nishiki Masayuki
Sugiyama Masafumi
Cho Tsuneo
Tsuchiya Taro
Ezaki Haruo
収録物名
Hiroshima Journal of Medical Sciences
32
1
開始ページ 9
終了ページ 14
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
A new type of activated charcoal for the direct hemoperfusion (DHP) has been developed for use in treatment of fulminant hepatic failure. Bead-type activated charcoal from petroleum pitch (BAC) was coated with polyetherurethane. The coating has permitted the charcoal to minimize the number of released microparticles and yet to show nearly the same adsorption performance as that of the non-coated BAC in vitro adsorption test. DHP using a fulminant hepatic failure dog induced by hepatic ischemia has shown improved consciousness and good biocompatibility as well as good clearance of toxic substances. As above, the newly developed bead-type activated charcoal coated with polyetherurethane can be considered effective in treatment of fulminant hepatic failure.
著者キーワード
Liver support system
Activated charcoal
Polyetherurethane
Hemoperfusion
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1983-03
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6863016