Zinc Content in Liver of Experimental Fulminant Hepatic Failure Rat : Significance as Index to Hepatic Injury and Regeneration
Hiroshima Journal of Medical Sciences 32 巻 3 号
305-309 頁
1983-09 発行
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| ファイル情報(添付) | |
| タイトル ( eng ) |
Zinc Content in Liver of Experimental Fulminant Hepatic Failure Rat : Significance as Index to Hepatic Injury and Regeneration
|
| タイトル ( jpn ) |
実験的急性肝不全ラットにおける肝亜鉛量の変動 : 肝障害及び再生の指標としての意義
|
| 作成者 |
Kawanishi Hideki
Nishiki Masayuki
Tsuchiya Taro
Ezaki Haruo
|
| 収録物名 |
Hiroshima Journal of Medical Sciences
|
| 巻 | 32 |
| 号 | 3 |
| 開始ページ | 305 |
| 終了ページ | 309 |
| 収録物識別子 |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| 抄録 |
A rat model of fulminant hepatic failure induced by D-galactosamine (Gal) was given glucagon and insulin. The amount of Zn contained in its liver was measured and investigated for use as an index to the progress of hepatic failure and to the hepatic regeneration.
The results showed that the Zn content in the rat's liver had been rapidly reduced to the lowest value 48 hours after Gal was given before the morphological change occurred. Also, a significant improvement was observed in the Zn content in liver by giving glucagon and insulin. As a result, it is suggested that the Zn content can be used as an index to the degree of hepatocyte injury and regeneration. |
| 著者キーワード |
Hepatic failure
Zn content in liver
Hepatocyte volume fraction
Insulin and glucagon
|
| NDC分類 |
医学 [ 490 ]
|
| 言語 |
英語
|
| 資源タイプ | 紀要論文 |
| 出版者 |
Hiroshima University School of Medicine
|
| 発行日 | 1983-09 |
| 出版タイプ | Version of Record（出版社版。早期公開を含む） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6358141
|
