Pre-Transplant Donor Specific Unresponsiveness in a Kidney Retransplant Recipient

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Title ( eng )
Pre-Transplant Donor Specific Unresponsiveness in a Kidney Retransplant Recipient
Title ( jpn )
ドナー特異的 unresponsiueness を呈した腎再移植症例
Creator
Dohi Kiyohiko
Ono Eiji
Fukuda Yasuhiko
Asahara Toshimasa
Yahata Hiroshi
Ezaki Haruo
Source Title
Hiroshima Journal of Medical Sciences
Volume 33
Issue 4
Start Page 775
End Page 777
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
A living related kidney transplant recipient, who showed very characterstic findings in immunologic study, was reported. This patient was a retransplant recipient. First graft of this patient was his mother's kidney, and the second graft was his older sister's kidney. HLA compatibility between the patient and the second donor was one haplotype identical. Although the patient was responsive in mixed-leukocyte-culture (MLC) against the second donor before first transplantation, MLC and cell-mediated-lympholysis (CML) tests before retransplantation showed specific unresponsiveness to the second donor. During 36 months after retransplantation, no rejection episodes nor any complications have been observed.
Keywords
Kidney transplantation
Mixed leukocyte culture
Immune tolerance
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University School of Medicine
Date of Issued 1984-12
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6398815