Influence of Hemoperfusion Using Polyetherurethane Sheet Embedded with Powdered Charcoal (UPC) on Middle Molecules of Hepatic Failure Dogs

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タイトル ( eng )
Influence of Hemoperfusion Using Polyetherurethane Sheet Embedded with Powdered Charcoal (UPC) on Middle Molecules of Hepatic Failure Dogs
タイトル ( jpn )
粉状活性炭シート(UPC)を用いた血液灌流による胚不全犬中分子量物質の変動
作成者
Kawanishi Hideki
Nishiki Masayuki
Kanao Motoo
Nakagawa Kenichi
Sugiyama Masafumi
Tsuchiya Taro
Ezaki Haruo
収録物名
Hiroshima Journal of Medical Sciences
33
4
開始ページ 633
終了ページ 638
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
Plasma taken from hepatic failure dogs induced by hepatic ischemia was used to observe the variation in its chromatogram obtained by conducting a high performance gel-chromatography (TSK G2000SW used). The progress of hepatic failure caused a distinct increase in the middle molecular (MM) fractions (m. w. over 500), which showed a good correlation with the condition of progressing hepatic failure. The reduction of the above number of peaks was observed when the hemoperfusion was performed using the polyetherurethane sheet embedded with powdered charocal (UPC) that had been newly developed mainly for the purpose of absorbing protein-bound substances. The UPC developed by the authors can successfully remove middle molecular substances in hepatic failure.
著者キーワード
Middle molecules
High performance gel-chromatography
Charcoal
UPC
Hemoperfusion
Liver support
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1984-12
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6534919