Removal of Adherent Bacteria from Catheter Materials in vitro by N-Acylated Amino Acids

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Title ( eng )
Removal of Adherent Bacteria from Catheter Materials in vitro by N-Acylated Amino Acids
Creator
Seo Kazushi
Nakano Hiroshi
Usui Tsuguru
Miyake Yoichiro
Suginaka Hidekazu
Source Title
Hiroshima Journal of Medical Sciences
Volume 39
Issue 4
Start Page 139
End Page 143
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
Indwelling urinary catheters may act as a reservoir of bacteria and cause urinary tract infections. Removal of the bacteria adherent to a urinary catheter should reduce the incidence of catheter-associated urinary tract infections. Using several N-acylated amino acids with combinations of four different acyl residues, we investigated their efficacy in removing adherent bacteria from catheter materials in vitro. Among them, acyl phenylalanine and acyl glycine (with acyl lengths of eight or ten) exhibited the highest ability to remove adherent bacteria.
Keywords
N-acylated amino acid
Bacterial adhesion
Catheter material
Urinary tract infection
Descriptions
This work was supported in part by the Tsuchiya Foundation for Medical Advancement.
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University Medical Press
Date of Issued 1990-12
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 2086565