Nucleotide Sequence of the 5' Region of the Human Platelet-derived Growth Factor A-chain Gene
Hiroshima Journal of Medical Sciences Volume 42 Issue 1
Page 47-52
published_at 1993-03
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| File | |
| Title ( eng ) |
Nucleotide Sequence of the 5' Region of the Human Platelet-derived Growth Factor A-chain Gene
|
| Creator |
Takimoto Yasuo
Li Wen Yu
Wang Zhao Yi
Tong Benton D.
Deuel Thomas F.
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 42 |
| Issue | 1 |
| Start Page | 47 |
| End Page | 52 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
We have isolated and characterized genomic clones of the 5' region of the human PDGF A-chain gene. The putative "TATAA" box was identified 876 bp upstream of the translation initiation site. A significant number of potential regulatory elements were identified in DNA sequences upstream of the "TATAA" box and were also found within the intrans sequenced. The DNA sequence results differ significantly from those reported for the PDGF B-chain gene, suggesting a basis for the expression of the PDGF A-chain gene and the B-chain gene under very different conditions.
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| Keywords |
PDGF-A chain
5'-Region
Nucleotide sequence
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University Medical Press
|
| Date of Issued | 1993-03 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 8486521
|
