Nucleotide Sequence of the 5' Region of the Human Platelet-derived Growth Factor A-chain Gene

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タイトル ( eng )
Nucleotide Sequence of the 5' Region of the Human Platelet-derived Growth Factor A-chain Gene
作成者
Takimoto Yasuo
Li Wen Yu
Wang Zhao Yi
Tong Benton D.
Deuel Thomas F.
収録物名
Hiroshima Journal of Medical Sciences
42
1
開始ページ 47
終了ページ 52
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
We have isolated and characterized genomic clones of the 5' region of the human PDGF A-chain gene. The putative "TATAA" box was identified 876 bp upstream of the translation initiation site. A significant number of potential regulatory elements were identified in DNA sequences upstream of the "TATAA" box and were also found within the intrans sequenced. The DNA sequence results differ significantly from those reported for the PDGF B-chain gene, suggesting a basis for the expression of the PDGF A-chain gene and the B-chain gene under very different conditions.
著者キーワード
PDGF-A chain
5'-Region
Nucleotide sequence
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University Medical Press
発行日 1993-03
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 8486521