A Study on the Lung Function in α1-antitrypsin-deficient (PiMZ) Patients

アクセス数 : 898
ダウンロード数 : 104

今月のアクセス数 : 12
今月のダウンロード数 : 3
ファイル情報(添付)
HiroshimaJMedSci_42_41.pdf 434 KB 種類 : 全文
タイトル ( eng )
A Study on the Lung Function in α1-antitrypsin-deficient (PiMZ) Patients
作成者
Kambe Masayuki
Morishita Kazuhiko
Tsubokura Tokuo
Tsuno Ken-ichiro
Kimura Toshiki
Utsumi Toshio
Kawamoto Hitoshi
Yamakido Michio
Mittman Charles
収録物名
Hiroshima Journal of Medical Sciences
42
1
開始ページ 41
終了ページ 45
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
Laurel and Eriksson published the first report indicating that a1-antitrypsin deficiency predisposed patients to the development of Chronic Obstructive Pulmonary Disease (COPD).

For the purpose of early detection, disturbances of pulmonary function in a1-antitrypsin mild deficiency cases (PiMZ) were compared with those of normal cases (PiMM) in caucasian Americans.

The marked results are as follows.
1) Parameters of flow-volume curves were more disturbed in PiMZ cases than in PiMM cases.
2) Volumes of isoflow are specially different between PiMZ and PiMM cases.
3) Mechanical properties, like lung work of breathing, were larger in PiMZ cases than in PiMM cases.
著者キーワード
Pulmonary emphysema
α1-antitrypsin
PiMZ type
Pulmonary function
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University Medical Press
発行日 1993-03
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 8486520