A Study on the Lung Function in α1-antitrypsin-deficient (PiMZ) Patients
Hiroshima Journal of Medical Sciences Volume 42 Issue 1
Page 41-45
published_at 1993-03
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| File | |
| Title ( eng ) |
A Study on the Lung Function in α1-antitrypsin-deficient (PiMZ) Patients
|
| Creator |
Kambe Masayuki
Morishita Kazuhiko
Tsubokura Tokuo
Tsuno Ken-ichiro
Kimura Toshiki
Utsumi Toshio
Kawamoto Hitoshi
Yamakido Michio
Mittman Charles
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 42 |
| Issue | 1 |
| Start Page | 41 |
| End Page | 45 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
Laurel and Eriksson published the first report indicating that a1-antitrypsin deficiency predisposed patients to the development of Chronic Obstructive Pulmonary Disease (COPD).
For the purpose of early detection, disturbances of pulmonary function in a1-antitrypsin mild deficiency cases (PiMZ) were compared with those of normal cases (PiMM) in caucasian Americans. The marked results are as follows. 1) Parameters of flow-volume curves were more disturbed in PiMZ cases than in PiMM cases. 2) Volumes of isoflow are specially different between PiMZ and PiMM cases. 3) Mechanical properties, like lung work of breathing, were larger in PiMZ cases than in PiMM cases. |
| Keywords |
Pulmonary emphysema
α1-antitrypsin
PiMZ type
Pulmonary function
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University Medical Press
|
| Date of Issued | 1993-03 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 8486520
|
