Malignant Paraganglioma Arising from the Posterior Mediastinum : A Case Report and Review of the Literature
Hiroshima Journal of Medical Sciences Volume 48 Issue 4
Page 123-127
published_at 1999-12
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| File | |
| Title ( eng ) |
Malignant Paraganglioma Arising from the Posterior Mediastinum : A Case Report and Review of the Literature
|
| Creator |
Isobe Takeshi
Oguri Tetsuya
Daga Haruko
Ishikawa Hisanobu
Ochiai Mari
Kitaguchi Souichi
Ishioka Shinichi
Yamakido Michio
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 48 |
| Issue | 4 |
| Start Page | 123 |
| End Page | 127 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
An unusual case of paraganglioma of posterior mediastinum occurred in a young adult with local recurrence and multiple distant metastasis. Because of its rarity, the determinants of prognosis factor between benign and malignant paraganglioma are uncertain. In this case, we investigated abnormalities of the p53 gene and ras gene mutations in tissues of primary and metastatic lesions. Neither abnormalities of p53 gene nor ras gene mutations were detected. The molecular approach is recommended as a means of clarifying the trend towards the malignancy of paraganglioma.
|
| Keywords |
Malignant paraganglioma
Posterior mediastinum
p53
ras
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University Medical Press
|
| Date of Issued | 1999-12 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
|
