Effects of Pentoxifylline on Sperm Motion Characteristics in Normozoospermic Men Defined by a Computer-aided Sperm Analysis
Hiroshima Journal of Medical Sciences 48 巻 4 号
117-121 頁
1999-12 発行
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| ファイル情報(添付) | |
| タイトル ( eng ) |
Effects of Pentoxifylline on Sperm Motion Characteristics in Normozoospermic Men Defined by a Computer-aided Sperm Analysis
|
| 作成者 |
Kinutani Masayuki
|
| 収録物名 |
Hiroshima Journal of Medical Sciences
|
| 巻 | 48 |
| 号 | 4 |
| 開始ページ | 117 |
| 終了ページ | 121 |
| 収録物識別子 |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| 抄録 |
This study was conducted to determine whether pentoxifylline has an in vitro effect on sperm motion characteristics in normozoospermic men. The subjects of the study were 15 male volunteers. After the spermatozoa were washed with mBWW medium, the sperm suspension was divided into two aliquots: one was treated with 1 mg/ml pentoxifylline, the other was used as a control. The sperm motion characteristics were examined by an HT-M2030 at 30, 60, 120, 180, 240 and 300 min during continuous exposure to the drug. As results, pentoxifylline increased the curvilinear velocity and the lateral head displacement. However, it did not affect sperm motility, the straight line velocity. Pentoxifylline may improve sperm fertilizing ability by altering the characteristics of sperm motion, not by increasing the number of motile spermatozoa.
|
| 著者キーワード |
Human
Spermatozoa
Motility analyzer
Pentoxifylline
|
| NDC分類 |
医学 [ 490 ]
|
| 言語 |
英語
|
| 資源タイプ | 紀要論文 |
| 出版者 |
Hiroshima University Medical Press
|
| 発行日 | 1999-12 |
| 出版タイプ | Version of Record（出版社版。早期公開を含む） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[ISSN] 0018-2052
[NCID] AA00664312
|
