Intractable Gastrointestinal Bleeding from Angiodysplasia in a Patient of Bernard-Soulier Syndrome : Report of a Case
Hiroshima Journal of Medical Sciences Volume 54 Issue 4
Page 113-115
published_at 2005-12
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Title ( eng ) |
Intractable Gastrointestinal Bleeding from Angiodysplasia in a Patient of Bernard-Soulier Syndrome : Report of a Case
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Creator |
Okita Riki
Konishi Kazuo
Osaki Akihiko
Yoshida Kazuhiro
Yamaguchi Yoshiyuki
Toge Tetsuya
Fujimura Kingo
Iwata Takashi
Sawamura Akihiro
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Source Title |
Hiroshima Journal of Medical Sciences
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Volume | 54 |
Issue | 4 |
Start Page | 113 |
End Page | 115 |
Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
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Abstract |
We herein report a case of gastrointestinal bleeding induced by angiodysplasia of the cecum in a case of Bernard-Soulier syndrome with recurrent breast cancer. In spite of endoscopic hemostatic therapy and interventional embolization, she had repeated massive bleeding from the cecal lesion. In addition, she had chronic hepatitis C and progressive liver tumors metastasized from breast cancer, and she finally died of hepatic failure. There are four case reports in the literature describing Bernard-Soulier syndrome with gastrointestinal bleeding angiodysplasia. The reported cases benefited from hormonal, endoscopical hemostasis and surgical therapy. In our case, because of her terminal metastatic breast cancer, only conservative treatments were administered after the third bleed. Both the endoscopic hemostatic method and interventional embolization showed only a temporary effect. Surgical treatment should be considered if the general condition can tolerate a surgical procedure.
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Keywords |
Bernard-Soulier syndrome
Gastrointestinal bleeding
Angiodysplasia
Interventional embolization
Breast cancer
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NDC |
Medical sciences [ 490 ]
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Language |
eng
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Resource Type | departmental bulletin paper |
Publisher |
Hiroshima University Medical Press
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Date of Issued | 2005-12 |
Rights |
Hiroshima University Medical Press
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Publish Type | Version of Record |
Access Rights | open access |
Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
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