Neck Circumference has Possibility as a Predictor for Metabolic Syndrome in Postmenopausal Women

Aoi Satomi

Miyake Takashi

Harada Toshihide

Ishizaki Fumiko

Ikeda Hiromi

Nitta Yumiko

Iida Tadayuki

Chikamura Chiho

Tamura Noriko

Nitta Kohsaku

Miyaguchi Hideki

Hiroshima Journal of Medical Sciences

[PISSN] 0018-2052

[EISSN] 2433-7668

[NCID] AA00664312

Subcutaneous fat depots play an important role in regulating metabolic profile in Japanese postmenopausal women. We investigated the possibility of neck circumference (NC) as a surrogate marker for metabolic disease risk estimates in Japanese postmenopausal women. We examined the association of NC with several markers of insulin resistance, lipid metabolism and atherosclerosis in 64 healthy postmenopausal women aged 63.6 ± 7.1 years in community-based samples in Japan. As a result, NC was significantly associated with indices of whole body obesity and visceral fat accumulation, such as body mass index (BMI) and waist circumference (WC). In the analysis of biomarkers for insulin resistance, NC was positively correlated to HbA1c, homeostasis model assessment ratio (HOMA-R) and leptin. In addition, an increase in triglycerides (TG) and a decrease in HDL-cholesterol (HDL-C) were also associated with NC. Interestingly, NC was also associated with atherosclerosis-related indices. The measurement of NC is an easy, inexpensive and reproducible method for assessment of obesity, and a possible predictor to identify the risk for future metabolic diseases in Japanese postmenopausal women.

Neck circumference

Obesity

Metabolic abnormality

BaPWV

医学 [ 490 ]

英語

Hiroshima University Medical Press

Copyright (c) Hiroshima University Medical Press

[ISSN] 0018-2052

[NCID] AA00664312