Six-year Experience of Permanent Prostate Brachytherapy for Clinically Localized Prostate Cancer
Hiroshima Journal of Medical Sciences Volume 60 Issue 3
Page 51-56
published_at 2011-09
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この文献の参照には次のURLをご利用ください : https://ir.lib.hiroshima-u.ac.jp/00034995
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HiroshimaJMedSci_60_51.pdf
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Title ( eng ) |
Six-year Experience of Permanent Prostate Brachytherapy for Clinically Localized Prostate Cancer
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Creator |
Kenjo Masahiro
Kobatake Kohei
Iwamoto Hideo
Goriki Akihiro
Oki Mami
Shoji Koichi
Miyamoto Katsutoshi
Masumoto Hiroshi
Kobayashi Kanao
Ohara Shinya
Murakami Yuji
Kaneyasu Yuko
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Source Title |
Hiroshima Journal of Medical Sciences
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Volume | 60 |
Issue | 3 |
Start Page | 51 |
End Page | 56 |
Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
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Abstract |
This report presents the outcome of prostate permanent brachytherapy (PPB). One hundred and seventy-two patients with clinically localized prostate cancer were treated with permanent brachytherapy using iodine-125 seeds (125-I) at Hiroshima University Hospital from July 2004 to June 2010. This study evaluated the efficacy of PPB in these patients. The median patient age was 69 years (range 53 to 82 years), the median prostate-specific antigen (PSA) value before biopsy was 6.75 ng/ml (range 3.5 to 47.9 ng/ml), and the median prostate volume was 23.1 ml (range 10.1 to 57 ml). The median follow-up was 37 months (range 1 to 72 months). The serum PSA levels decreased continuously after PPB throughout the entire follow-up period in 97% of patients without neoadjuvant hormonal therapy. No relapse occurred during the follow-up period in patients at low risk. Our 6-year experience suggests that PPB is effective for localized prostate cancer. Patients with prostate cancer that does not require combined External beam radiation therapy (EBRT) have the best chance of responding to treatment.
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Keywords |
Brachytherapy
Localized prostate cancer
Iodine-125 seed
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NDC |
Medical sciences [ 490 ]
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Language |
eng
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Resource Type | departmental bulletin paper |
Publisher |
Hiroshima University Medical Press
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Date of Issued | 2011-09 |
Rights |
(c) Hiroshima University Medical Press.
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Publish Type | Version of Record |
Access Rights | open access |
Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
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