Biomolecule detection based on Si single-electron transistors for highly sensitive integrated sensors on a single chip
Applied Physics Letters Volume 100 Issue 2
Page 023704-
published_at 2012
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| File | |
| Title ( eng ) |
Biomolecule detection based on Si single-electron transistors for highly sensitive integrated sensors on a single chip
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| Creator |
Kudo Takashi
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| Source Title |
Applied Physics Letters
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| Volume | 100 |
| Issue | 2 |
| Start Page | 023704 |
| Abstract |
Biomolecule detection was achieved using a Si single-electron transistor (SET) for highly-sensitive detection. A multiple-island channel-structure was used for the SET to enable room-temperature operation and to increase sensitivity. Coulomb oscillation shifted against the gate voltage due to biotin-streptavidin binding. Coulomb oscillation has a possibility to increase transconductance (gm), and a higher gm leads to greater sensitivity to a charged target. Since a Si structure is important for integrating label-free-biomolecule and/or ion sensors into large-scale-integrated circuits, a Si SET with multiple islands should enable the integration of a sensor system on a single chip for multiplexed detections and simultaneous diagnoses.
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| NDC |
Electrical engineering [ 540 ]
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| Language |
eng
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| Resource Type | journal article |
| Publisher |
American Institute of Physics
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| Date of Issued | 2012 |
| Rights |
(c) 2012 American Institute of Physics
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| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0003-6951
[DOI] 10.1063/1.3676664
[NCID] AA00543431
[DOI] http://dx.doi.org/10.1063/1.3676664
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