Malignant peripheral nerve sheath tumor arising from the greater omentum: Case report

World journal of surgical oncology Volume 9 Page 33- published_at 2011-03-21
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Title ( eng )
Malignant peripheral nerve sheath tumor arising from the greater omentum: Case report
Creator
Miguchi Masashi
Takakura Yuji
Adachi Tomohiro
Kawaguchi Yasuo
Shinomura Manabu
Tokunaga Masakazu
Okajima Masazumi
Source Title
World journal of surgical oncology
Volume 9
Start Page 33
Abstract
Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft tissue tumors that arise from a peripheral nerve or exhibit nerve sheath differentiation. Most of these tumors arise on the trunk, extremities, or head and neck regions; they are very rarely located in the abdominal cavity. The patient was a 71-year-old man who was referred to our hospital for a mass and pain in the right lower abdomen. Abdominal computed tomography revealed a large (9 × 9 cm), well-circumscribed, lobulated, heterogeneously enhanced mass in the pelvis. Exploratory laparotomy revealed a large mass in the greater omentum, and the tumor was completely excised. Histopathological analysis revealed that the tumor was composed of spindle cells with high mitotic activity. On staining the tumor, positive results were obtained for S-100 but negative results were obtained for c-kit, cluster of differentiation (CD)34, α-smooth muscle actin, and desmin. These findings strongly supported a diagnosis of MPNST primarily arising from the greater omentum. To the best of our knowledge, this is the first reported case of an MPNST arising from the greater omentum. In this report, we have described the case of a patient with an MPNST arising from the greater omentum and have discussed the clinical characteristics and management of MPNSTs.
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type journal article
Publisher
BioMed Central
Date of Issued 2011-03-21
Rights
Copyright (c) 2011 Miguchi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Publish Type Version of Record
Access Rights open access
Source Identifier
[DOI] 10.1186/1477-7819-9-33
[NCID] AA12048269
[DOI] http://dx.doi.org/10.1186/1477-7819-9-33