Functional interactions between the cerebellum and the premotor cortex for error correction during the slow rate force production task : an fMRI study

Experimental Brain Research Volume 193 Issue 1 Page 143-150 published_at 2009-02
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Title ( eng )
Functional interactions between the cerebellum and the premotor cortex for error correction during the slow rate force production task : an fMRI study
Creator
Fujimura Naoki
Maruishi Masaharu
Muranaka Hiroyuki
Source Title
Experimental Brain Research
Volume 193
Issue 1
Start Page 143
End Page 150
Abstract
Although neuroimaging studies indicate that fMRI signal changes in the cerebellum (CB) during the performance of a target movement reflect functions of error detection and correction, it is not well known how the CB intervenes in task-demanded movement attributes during automated on-line movement, i.e., how the CB simultaneously coordinates movement rate and error correction. The present study was undertaken to address this issue by recording fMRI signals during the performance of a task at two different movement rates (0.4 Hz and 0.8 Hz). The results showed that movement errors increased with increasing movement rates. We also demonstrated that activation of the left CB increased with decreasing movement rates, whereas activation of the ipsilateral (right) premotor cortex (PMC) increased with increasing movement rates. Furthermore, there were significant relationships between individual movement errors and left CB activation at both movement rates, but these relationships were not observed in the ipsilateral PMC. Taken together, it is suggested that during the performance of automated and well-controlled slow force-production tasks, the interactions between cortical (right PMC) and subcortical (left CB) motor circuits, i.e., a functional dissociation between PMC and CB, is exclusively dedicated to controlling movement rate and error correction. In particular, the present results showing significant relationships between individual force-control errors and CB activation might reflect functional differences of an individual's internal model.
Keywords
Force production task
movement rate
error correction
fMRI
cerebellum
premotor cortex
NDC
Electrical engineering [ 540 ]
Language
eng
Resource Type journal article
Publisher
Springer Berlin
Date of Issued 2009-02
Rights
Copyright (c) 2009 Springer
Publish Type Author’s Original
Access Rights open access
Source Identifier
The original publication is available at www.springerlink.com
[ISSN] 0014-4819
[DOI] 10.1007/s00221-008-1682-4
[NCID] AA00640970
[DOI] http://dx.doi.org/10.1007/s00221-008-1682-4