Expression of cell-cycle regulators during Xenopus oogenesis

Gene Expression Patterns 3 巻 2 号 165-168 頁 2003-05 発行
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タイトル ( eng )
Expression of cell-cycle regulators during Xenopus oogenesis
作成者
Kawasaki Ayako
Sagata Noriyuki
収録物名
Gene Expression Patterns
3
2
開始ページ 165
終了ページ 168
抄録
In full-grown Xenopus oocytes, cell-cycle regulators and an inactive form of maturation/M phase promoting factor (pre-MPF) are stored ready to bring about a specific cell cycle for oocyte maturation. We examined the expression pattern of these cell-cycle regulators as well as pre-MPF formation during oogenesis. Cdc2 and Cyclin B2 were already present in stage I oocytes and pre-MPF formation was also detected in stage I oocytes. Some negative regulators of MPF, Myt1 and Chk1, were synthesized early in oogenesis. In contrast, positive regulators of MPF, MEK, MAPK and Cdc25C, were mainly synthesized late in oogenesis. Northern blotting analysis suggested that the synthesis of these cell-cycle regulators was controlled by translation.
著者キーワード
Xenopus
oogenesis
cell-cycle regulator
言語
英語
資源タイプ 学術雑誌論文
出版者
Elsevier Science B.V.
発行日 2003-05
権利情報
Copyright (c) 2003 Elsevier Science B.V.
出版タイプ Author’s Original(十分な品質であるとして、著者から正式な査読に提出される版)
アクセス権 オープンアクセス
収録物識別子
[NCID] AA11800332
[ISSN] 1567-133X
[DOI] 10.1016/S1567-133X(03)00037-1
[DOI] http://dx.doi.org/10.1016/S1567-133X(03)00037-1 ~の異版である