CT perfusion imaging for childhood moyamoya disease before and after surgical revascularization

Sakamoto Shigeyuki

Ohba Shinji

Shibukawa Masaaki

Kiura Yoshihiro

Arita Kazunori

Kurisu Kaoru

Acta Neurochirurgica

Moyamoya disease is a progressive occlusive disease of the circle of Willis with prominent collateral arterial formation. We report on a 12-year-old girl with moyamoya disease presenting with transient ischemic attacks (TIAs). Surgical indirect revascularization was performed. The patient did not suffer further TIAs at 12 month follow-up. Pre and postoperative cerebral perfusion were studied in quantitative single photon emission computerized tomography (SPECT) and CT perfusion imaging. CT perfusion imaging demonstrated postoperative increased cerebral blood flow as well as SPECT before and after revascularization. Furthermore, the area of decreased vascular reserve in SPECT with acetazolamide corresponded with areas of increased cerebral blood volume in CT perfusion imaging. CT perfusion imaging was equivalent to SPECT in accuracy, and superior in spatial resolution. CT perfusion imaging is likely to become more widely available as an easy-to-perform technique for assessing cerebral perfusion in a patient with moyamoya disease.

childhood

CT perfusion image

moyamoya disease

SPECT

Medical sciences [ 490 ]

eng

Springer

Copyright (c) 2006 Springer-Verlag. "The original publication is available at www.springerlin.com"

[ISSN] 0001-6268

[DOI] 10.1007/s00701-005-0634-z

[NCID] AA0050885X

[PMID] 16184319

[DOI] http://dx.doi.org/10.1007/s00701-005-0634-z isVersionOf