The cDNA sequence and expression of the AAA-family peroxin genes pex-1 and pex-6 from the nematode Caenorhabditis elegans
Zoological Science 18 巻 5 号
675-681 頁
2001 発行
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| ファイル情報(添付) | |
| ファイル情報(添付) | |
| タイトル ( eng ) |
The cDNA sequence and expression of the AAA-family peroxin genes pex-1 and pex-6 from the nematode Caenorhabditis elegans
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| 作成者 |
Ghenea Simona
Takeuchi Masaki
Motoyama Junko
Sasamoto Kumiko
Kunau Wolf-H.
Kamiryo Tatsuyuki
Bun-ya Masanori
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| 収録物名 |
Zoological Science
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| 巻 | 18 |
| 号 | 5 |
| 開始ページ | 675 |
| 終了ページ | 681 |
| 抄録 |
We cloned cDNAs encoding two peroxins, PEX-1 and PEX-6, of the nematode Caenorhabditis elegans. Peroxins are proteins that play essential roles in peroxisome biogenesis and are encoded by pex genes. Among the peroxins, PEX-1 and PEX-6 constitute the subfamily 2 of AAA (ATPases associated with diverse cellular activities) proteins. Each cDNA agreed well with the respective mRNA in size (3.4 kb for pex-1 and 2.3 kb for pex-6) and did not carry any spliced leader sequence. The pex-1 cDNA was composed of 24 exons, which were encoded by a genomic region containing three open reading frames (ORFs), c11h1.4, c11h1.5, and c11h1.6; the predicted ORF c11h1.5 was encompassed in the 15th intron. Although many exon-intron borders in pex-1 were inconsistent with those predicted for c11h1.4 and c11h1.6, those in pex-6 coincided with those for the ORF f39g3.7. The pex-1 and pex-6 genes encoded proteins with 996 and 720 amino acid residues, respectively. Both pex-1 mRNA and pex-6 mRNA were detectable mainly in intestinal cells throughout the life cycle of C. elegans.
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| 内容記述 |
The erratam is attached for this article.
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| NDC分類 |
生物科学・一般生物学 [ 460 ]
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| 言語 |
英語
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| 資源タイプ | 学術雑誌論文 |
| 出版者 |
Zoological Society of Japan
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| 発行日 | 2001 |
| 権利情報 |
Copyright (c) 2001 Zoologogical Society of Japan
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| 出版タイプ | Author’s Original（十分な品質であるとして、著者から正式な査読に提出される版） |
| アクセス権 | オープンアクセス |
| 収録物識別子 |
[ISSN] 0289-0003
[DOI] 10.2108/zsj.18.675
[DOI] http://dx.doi.org/10.2108/zsj.18.675
～の異版である
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