We provided anesthesia care for 25 patients in an open MRI operating room and summarized here our experience. When surgeons use MRI during surgery, the presence of noise in the images caused by other electronic equipment in the area often hinders accurate diagnosis. In addition, malfunction of monitoring and anesthesia equipment during surgery due to the MRI magnetic field created during an MR examination can occur. In order to prevent imaging interference affecting equipment not compatible with MRI, we utilized 2 specially prepared shield boxes and wrapped the personal computer used for coordinating the data with a mesh-like cloth made by Ixol-mesh. In addition, we prepared a shielded operating room in order to block noise from the outside. To prevent malfunction of the surgical and electronic instruments, we kept them outside the magnetic field of 5 Gauss or lower to minimize the magnetic effect generated with MRI. Furthermore, patient safety during MRI imaging was improved by establishing a wireless communication system to feed data from medical devices, which allowed elimination of cabling.