Comparative Study between Nude Mice and Immunosuppressed Hamsters as Recipients of Human Tumor Xenografts

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タイトル ( eng )
Comparative Study between Nude Mice and Immunosuppressed Hamsters as Recipients of Human Tumor Xenografts
作成者
NAOMOTO Yoshio
TANAKA Noriaki
KONDO Hidenori
MOTODA Ryuichi
ANDO Shunsaku
KURIMOTO Masasi
ORITA Kunzo
収録物名
Hiroshima Journal of Medical Sciences
36
3
開始ページ 305
終了ページ 308
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
We comparatively examined nude mice and hamsters as to their suitability as recipients of human cancers. CD-1 nude mice and golden hamsters immunosuppressed with anti-hamster thymocyte serum were used. Nude mice were superior in the areas of primary transplantation and subsequent transfer and maintenance. However, growth of tumors transplantable to both animals (a lung cancer line LC-1, a colon cancer line RPMI4788) tends to be better in hamsters than in nude mice. The better development of LC-1 and RPMI4 788 cells in hamsters than in nude mice appears to be related to the superior gain in body weight shown by hamsters.
著者キーワード
Nude mouse
Hamster
Human tumor
Xenograft
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University Medical Press
発行日 1987-09
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3692895