Protective effects of a water-soluble extract from cultured medium of Gall o de rIll a luciduln (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3Fl mice : Increased small intestinal crypt survival and prolongation of average time to anilnaI death
International Journal of Molecular Medicine 15 巻 3 号
401-406 頁
2005-03 発行
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ファイル情報(添付) | |
タイトル ( eng ) |
Protective effects of a water-soluble extract from cultured medium of Gall o de rIll a luciduln (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3Fl mice : Increased small intestinal crypt survival and prolongation of average time to anilnaI death
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作成者 |
Kubo Nanami
Myojin Yuki
Shimamoto Fumio
Kashimoto Naoki
Kyo Eikai
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収録物名 |
International Journal of Molecular Medicine
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巻 | 15 |
号 | 3 |
開始ページ | 401 |
終了ページ | 406 |
抄録 |
Radioprotective effects of a water-soluble extracts from cultured medium of Ganoderma lucidum (Rei-shi) mycelia (designed as MAK) and Agaricus blazei (Agaricus) against the shortening of survival time or the injury of crypt by X-irradiation were investigated in male B6C3F1 mice. MAK and Agaricus at three different doses were mixed into basal diet into biscuits at 5, 2.5 and 1.25% and administered from 1 week before irradiation. MAK (5% group) significantly prolonged animal survival as compared with basal diet group (control group) after 7 Gy of X-ray irradiation at a dose rate of 2 Gy min-1. At doses of 8, 10 and 12 Gy X-irradiation at a dose rate of 4 Gy min-1 MAK (5% group) significantly increased crypt survival as compared to other groups. These results suggest that MAK can act as a radioprotective agent.
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著者キーワード |
radiation protection
crypt survival
survival
Ganoderma luciduml (Rei-shi) mycelia
Agaricus blazei
B6C3F1 mouse
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NDC分類 |
医学 [ 490 ]
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言語 |
英語
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資源タイプ | 学術雑誌論文 |
出版者 |
Spandidos Publications Ltd.
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発行日 | 2005-03 |
権利情報 |
Copyright (c) 2005 Spandidos Publications Ltd.
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出版タイプ | Version of Record(出版社版。早期公開を含む) |
アクセス権 | オープンアクセス |
収録物識別子 |
[ISSN] 1107-3756
[NCID] AA11445762
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