Elevation of Ammonia Contents in the Cerebral Hemisphere under the Blood-Brain Barrier Opening

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Title ( eng )
Elevation of Ammonia Contents in the Cerebral Hemisphere under the Blood-Brain Barrier Opening
Creator
WATANABE Akiharu
FUJIWARA Masachika
TOMINAGA Satoru
NAGASHIMA Hideo
Source Title
Hiroshima Journal of Medical Sciences
Volume 36
Issue 4
Start Page 415
End Page 416
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
Elevation of ammonia contents was observed 1 hr following infusion of 4% ammonium acetate only in the cerebral hemisphere where reversible opening of the blood-brain barrier was induced by intracarotid injection of 0.1% deoxycholic acid. This finding suggests that ammonia may contribute to hepatic encephalopathy, when the permeability of the blood-brain barrier is altered.
Keywords
Brain ammonia
Blood-brain barrier
Hyperammonemia
Bile acid
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University Medical Press
Date of Issued 1987-12
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3448063