Comparative Study between Nude Mice and Immunosuppressed Hamsters as Recipients of Human Tumor Xenografts
Hiroshima Journal of Medical Sciences Volume 36 Issue 3
Page 305-308
published_at 1987-09
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| File | |
| Title ( eng ) |
Comparative Study between Nude Mice and Immunosuppressed Hamsters as Recipients of Human Tumor Xenografts
|
| Creator |
NAOMOTO Yoshio
TANAKA Noriaki
KONDO Hidenori
MOTODA Ryuichi
ANDO Shunsaku
KURIMOTO Masasi
ORITA Kunzo
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 36 |
| Issue | 3 |
| Start Page | 305 |
| End Page | 308 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
We comparatively examined nude mice and hamsters as to their suitability as recipients of human cancers. CD-1 nude mice and golden hamsters immunosuppressed with anti-hamster thymocyte serum were used. Nude mice were superior in the areas of primary transplantation and subsequent transfer and maintenance. However, growth of tumors transplantable to both animals (a lung cancer line LC-1, a colon cancer line RPMI4788) tends to be better in hamsters than in nude mice. The better development of LC-1 and RPMI4 788 cells in hamsters than in nude mice appears to be related to the superior gain in body weight shown by hamsters.
|
| Keywords |
Nude mouse
Hamster
Human tumor
Xenograft
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University Medical Press
|
| Date of Issued | 1987-09 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3692895
|
