Cellular Immunity of Patients with Lung Cancer and Other Lung Diseases II. Analysis of interleukin-2 production

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Title ( eng )
Cellular Immunity of Patients with Lung Cancer and Other Lung Diseases II. Analysis of interleukin-2 production
Creator
FUJIWARA Saeko
AKIYAMA Mitoshi
KOBUKE Kyoko
HAKODA Masayuki
YAMADA Michiko
SASAKI Hideo
NERIISHI Kazuo
KOHNO Nobuoki
HOSODA Yutaka
TAKAISHI Masatoshi
YAMAKIDO Michio
Source Title
Hiroshima Journal of Medical Sciences
Volume 36
Issue 2
Start Page 199
End Page 204
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
Interleukin-2 (IL-2) production by stimulated peripheral blood lymphocytes (PBL) from patients with lung cancer and noncancerous respiratory diseases was determined. The results are as follows:
1) Neither sex nor age difference was observed for IL-2 production among healthy people.
2) IL-2 production showed a positive correlation with the Leu-3a/Leu-2a ratio and a negative correlation with the percentage of HLA-DR+ cells.
3) IL-2 production of patients with lung cancer and noncancerous respiratory diseases did not differ from that of healthy persons.
4) No difference in IL-2 production was found in relation to the clinical stage of lung cancer, but subjects with low IL-2 production were mostly observed in the advanced stage group (Stage IV).
Keywords
Lung cancer
Interleukin-2
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima Journal Medical Press
Date of Issued 1987-06
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3498711