Changes in Blood Coagulation and Fibrinolysis Systems after Hassab's Procedure for Portal Hypertension

TANAKA Tsuneo

ICHIBA Yasuyuki

SEIKOH Rokuro

TAKEUCHI Hitoshi

ITOH Nobuaki

KODAMA Osamu

DOHI Kiyohiko

Hiroshima Journal of Medical Sciences

[PISSN] 0018-2052

[EISSN] 2433-7668

[NCID] AA00664312

The changes in the coagulation and fibrinolysis systems in 12 patients on whom Hassab's procedure was given for portal hypertension with liver cirrhosis (LC) were studied. The coagulation factors such as the platelet count, prothrombin time (PT) and fibrinogen level showed reduction before operation, while after operation these values showed significant increase. Whereas the fibrinolysis, the fibrinogen degradation products (FDP) showed no positive cases before operation, but after operation a significant rise was noted on the 7th day as the peak. It was observed from these findings that Hassab's procedure given on the cases with LC induced acceleration in the coagulation and fibrinolysis systems after operation, so that ample care should be taken for the complications including disseminated intravascular coagulation (DIC) or gastrointestinal bleeding.

Blood coagulation and fibrinolysis system

Portal hypertension

Medical sciences [ 490 ]

eng

Hiroshima University School of Medicine

[ISSN] 0018-2052

[NCID] AA00664312

[PMID] 4066402