Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b HCV with drug resistance-associated variants in prior DAA treatment failures and human hepatocyte transplanted mice 1.Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures 2.Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice

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Title ( eng )
Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b HCV with drug resistance-associated variants in prior DAA treatment failures and human hepatocyte transplanted mice 1.Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures 2.Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice
Title ( jpn )
直接作用型抗ウイルス薬治療不成功例とヒト肝細胞移植マウスにおける薬剤耐性変異を伴うジェノタイプ1b型C型肝炎ウイルスに対するグレカプレビル/ピブレンタスビル治療の有効性の研究 1.実臨床における直接作用型抗ウイルス薬治療不成功C型肝炎患者に対するグレカプレビル/ピブレンタスビルの有効性の検討 2.ヒト肝細胞移植マウスを用いた薬剤耐性変異を伴うジェノタイプ1b型C型肝炎ウイルスに対するグレカプレビル/ピブレンタスビル治療の有効性の検討
Creator
Oosawa Mitsutaka
Descriptions
内容の要旨, 審査の要旨
Language
eng
Resource Type doctoral thesis
Rights
(c) Japanese Society of Gastroenterology 2018
(c) 2019 The Authors
Access Rights open access
Source Identifier
Osawa, M., Imamura, M., Teraoka, Y. et al. Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures. J Gastroenterol 54, 291-296 (2019)
Journal of General Virology, 2019, Volume 100, Issue 7, 001268
[DOI] https://doi.org/10.1007/s00535-018-1520-9
[DOI] https://doi.org/10.1099/jgv.0.001268
Dissertation Number 甲第8170号
Degree Name
Date of Granted 2020-03-23
Degree Grantors
広島大学
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