Formation of β‐(1,3‐1,6)‐D‐glucan‐complexed [70]fullerene and its photodynamic activity towards macrophages
Organic and Biomolecular Chemistry Volume 15 Issue 9
Page 1990-1997
published_at 2017-03-01
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| File | |
| Title ( eng ) |
Formation of β‐(1,3‐1,6)‐D‐glucan‐complexed [70]fullerene and its photodynamic activity towards macrophages
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| Creator |
Akiyama Motofusa
Koumoto Kazuya
Kagoshima Yuta
Li Jiawei
Suzuki Toshio
Nagasaki Takeshi
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| Source Title |
Organic and Biomolecular Chemistry
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| Volume | 15 |
| Issue | 9 |
| Start Page | 1990 |
| End Page | 1997 |
| Abstract |
[70]Fullerene was dissolved in water by the complexation with β‐1,3‐glucan using a mechanochemical high‐speed vibration milling apparatus. The photodynamic activity of β‐1,3 glucan‐complexed C70 was highly dependent on the expression level of dectin‐1 on the cell surfaces of macrophages. The photodynamic activity increased as a result of a synergistic effect between β‐1,3‐glucan‐complexed 1’‐acetoxychavicol acetate and the C70 complex.
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| Descriptions |
This work was supported by JSPS KAKENHI Grant‐in‐Aid for Scientific Research (B) (Grant No. JP16H04133), Grant‐in‐Aid for Scientific Research (C) (Grant No. 26350528) and Grant‐in‐Aid for Challenging Exploratory Research (Grant No. JP16K13982).
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| NDC |
Chemistry [ 430 ]
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| Language |
eng
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| Resource Type | journal article |
| Publisher |
Royal Society of Chemistry
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| Date of Issued | 2017-03-01 |
| Rights |
Copyright (c) 2017 The Royal Society of Chemistry
This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
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| Publish Type | Author’s Original |
| Access Rights | open access |
| Source Identifier |
[ISSN] 1477-0520
[DOI] 10.1039/c6ob02747d
[PMID] 28177008
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