Lipid-membrane-incorporated arylboronate esters as agents for boron neutron capture therapy

Organic and Biomolecular Chemistry Volume 15 Issue 7 Page 1565-1569 published_at 2017-02-21
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Title ( eng )
Lipid-membrane-incorporated arylboronate esters as agents for boron neutron capture therapy
Creator
Ashizawa Kengo
Koumoto Kazuya
Nagasaki Takeshi
Source Title
Organic and Biomolecular Chemistry
Volume 15
Issue 7
Start Page 1565
End Page 1569
Abstract
Arylboronate esters bearing methyl groups in both of their ortho positions were stably incorporated into lipid membranes at high concentrations without undergoing hydrolysis to the corresponding boronic acids. This method could be used in combination with previous methods to increase the maximum ratio of boron atoms in liposomal boron carriers.
Descriptions
This work was supported by a JSPS KAKENHI Grant-in-Aid for Scientific Research (B) (Grant No. JP16H04133) and a Grant-in-Aid for Challenging Exploratory Research (Grant No. JP16K13982).
NDC
Chemistry [ 430 ]
Language
eng
Resource Type journal article
Publisher
Royal Society of Chemistry
Date of Issued 2017-02-21
Rights
Copyright (c) 2017 The Royal Society of Chemistry
This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
Publish Type Author’s Original
Access Rights open access
Source Identifier
[ISSN] 1477-0520
[DOI] 10.1039/c6ob02142e
[PMID] 27824199