OPSONIC ACTIVITY OF AGAMMAGLOBULINEMIA SERUM DETERMINED BY OXYGEN CONSUMPTION CAPACITY OF LEUKOCYTES

Hiroshima Journal of Medical Sciences Volume 30 Issue 3 Page 243-246 published_at 1981-09-10
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Title ( eng )
OPSONIC ACTIVITY OF AGAMMAGLOBULINEMIA SERUM DETERMINED BY OXYGEN CONSUMPTION CAPACITY OF LEUKOCYTES
Title ( jpn )
好中球酸素消費能により測定した無ガンマグログリン血症血清のオプソニン活性
Creator
Kobayashi Yohnosuke
Sakano Takashi
Hayashi Kazunari
Usui Tomofusa
Source Title
Hiroshima Journal of Medical Sciences
Volume 30
Issue 3
Start Page 243
End Page 246
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
In evaluating the therapeutic efficacy of gammaglobulin preparations in patients with agammaglobulinemia, opsonic activity of patients' sera in terms of oxygen consumption capacity of normal leukocytes is advocated as a useful index. Although the serum IgG level is a commonly used indicator, its determination alone was found out not always to reflect antibody levels in such sera. The method described here is simple and gives quantitative results and deserves a wider trial in controlling gammaglobulin replacement therapy.
Descriptions
This work was supported in part by a Grant-in-Aid from the Japan Medical Research Foundation and Grants-in-Aid (Projects NO. 157253 and 544050) from the Ministry of Education, Science and Culture of Japan.
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University School of Medicine
Date of Issued 1981-09-10
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6170608